Your need for noise reduction depends very much on the way you process your photos. Especially HDR processing can create an enormous amount of noise, which has to be dealt with. There are different ways you can do this and I think Imagenomic is one of the best.
Imagenomic Noiseware gives you a big amount of sliders you can push around to remove noise, but in the years I’ve been using it, I never used one. I bet that will make the results better, but the results you get just using the first two under Noise level are good enough in almost all cases.
I also never use it at strong settings. The values go from -20 to +20 and I usually don’t go above 0 for most of my photos. In the sample screenshots I included different situations with different settings.
Recently with Lightroom noise reduction getting much better, the need for a separate noise reduction plugins was not that big. But for some photos, Lightroom can remove very much detail when removing noise. Noiseware can have better results there. I personally use both, Lightroom noise reduction by weaker noise, Imagenomic by stronger noise. Sometimes even both, Lightroom for the initial noise reduction and Imagenomic for finishing touches.
Btw. same as with all noise reduction, be careful not to overdo it. It can remove photo detail and also introduce color banding into your photos.
You can find more information on the plugin on the Imagenomic Noiseware site.